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Granted De Novo Authorization

Designed to Enhance the Clinical Value of Red Blood Cells

The Hemanext ONE® Red Blood Cell (RBC) Processing and Storage system limits oxygen, the fuel for oxidative damage, providing a higher quality blood product.1,2,3

1. Rabcuka J, Blonski S, Meli A, et al. Metabolic reprogramming under hypoxic storage preserves faster oxygen unloading from stored red blood cells. Blood Adv. 2022; 6(18):5415-5428. doi: 10.1182/bloodadvances.2022007774. 2. Reisz J, Wither M, Dzieciatkowska M, et al. Oxidative modifications of glyceraldehyde 3-phosphate dehydrogenase regulate metabolic reprogramming of stored red blood cells. Blood. 2016;128: e32-42. 3. HEMANEXT ONE® (Blood container set used to process and store CP2D/AS-3 Red Blood Cells, Leukocytes Reduced, and O2/CO2 Reduced) [US Instructions for Use]. Lexington, MA: Hemanext Inc.

Science & Innovation Forum – Pros & Cons of Big & Small Data in RBC Biology Followed by: Perspectives on A New Innovation in RBC Processing and Storage

Please note: AABB reserves the right to make updates to this program.
When: Thursday, November 30, 2023, 2:00 – 3:00 PM (ET)

Presented by Hemanext®, an AABB Premium Corporate Partner.

Latest News & Events


Current and prospective investors  access to the investor Portal

COVID 19 Updates

Follow the course of COVID-19 and locate where to donate blood

Educational Symposiums

View educational material and interesting presentations

Our Science

Learn about the journey of red blood cells after donation including degradation that occurs during storage and discover the potential of hypoxic storage to alleviate this problem.

Stored Blood

The average human body stores about 5.6 liters of blood. As it circulates through the body several times each minute, it accomplishes a variety of functions.

Storage Lesion

The existence of the storage lesion process has been well established, and recent scientific work has increased the precision and depth.

Clinical Implications

Numerous studies pertaining to clinical implications of storage lesion suggest a linkage to hyper-coagulability, inflammation, impaired perfusion, immuno-modulation, organ dysfunction13, and mortality14.

Hypoxic Storage

Hemanext is developing a technology to enable the storage of RBC under hypoxic conditions. Removing O2 during storage removes the primary “fuel” for oxidative stress1-11.

Hemanext Research

Learn more about Hemanext and take a closer look at our publications, studies, and posters focused on blood quality and red blood cell characterization.

Worldwide Patent Assets

Accepted Scientific Abstracts

Total Publications


We are happy to answer any questions about the company, our technology, or our research. Please fill out the form below and we will connect with you!